Genetic Archives on Metabolism & Transporters


1) The Human Cytochrome P450 (CYP) Allele Nomenclature Database (http://www.cypalleles.ki.se)

Overseen by The Human Cytochrome P450 (CYP) Allele Nomenclature Committee, the main purpose of the Human Cytochrome P450 (CYP) Allele Nomenclature website is the management of an official and unified allele designation system, as well as the provision of a database of CYP alleles and their associated effects.  Inclusion criteria are summarized at http://www.cypalleles.ki.se/criteria.htm.

Additional information by Sim SC, Ingelman-Sundberg M. Update on allele nomenclature for human cytochromes P450 and the Human Cytochrome P450 Allele (CYP-allele) NomenclatureDatabase. Methods Mol Biol 2013;987:251-9.

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Provided by the University of California, San Francisco Pharmacogenetics of Membrane Transporters (PMT) Project, this database provides provides information on genetic variants (including single nucleotide polymorphisms (SNPs) and insertions/deletions) in membrane transporter genes that have been discovered by the PMT project. Additional information by Morrissey KM et al. The UCSF-FDA TransPortal: a public drug transporter database. Clin Pharmacol Ther. 2012;92:545-6.

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The database of Arylamine N-acetyltransferases (NATs) contains information relevant to the consensus nomenclature of human and non-human  NATgenes and alleles in humans and other organisms.  These databases are intended to be a useful resource to study the genetic, evolutionary and functional diversity of the NAT isoenzymes.

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To suggest additions please contact the Science Gateway administrator at sgwadmin@africa-grid.org.